Indirectly, yes. An “increase” in glutathione levels improves ATP production. When glutathione gets too low in the muscle cells, the levels of oxidizing free radicals rise. These react with parts of the cell’s “machinery” (mitochondria), lowering their output of ATP. So the muscle cells then experience an energy crisis, causing fatigue. Over time, more problems accumulate in the mitochondria because of the lack of sufficient glutathione. These issues include toxins, viral DNA, and mineral imbalances… a vicious cycle.